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14

抑制剂 & 化合物

6

天然产物

46

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T36533	SCH 725674
	SCH 725674 is an antifungal macrolide originally isolated from Aspergillus. It inhibits the growth of S. cerevisiae and C. albicans in vitro (MICs = 8 and 32 μg/ml, respectively).
T35769	Blasticidin A
	Blasticidin A is a bacterial metabolite originally isolated from S. resistomycificus strain 2A-327. It inhibits aflatoxin production by A. parasiticus without affecting fungal growth (IC50s = 0.25 and 1.6 μM, respectively). Blasticidin A also decreases ribosomal protein levels and inhibits protein synthesis in S. cerevisiae.
T35574	Adenosine 5'-phosphosulfate (sodium salt)
	Adenosine 5'-phosphosulfate is an ATP and sulfate competitive inhibitor of ATP sulfurylase in humans, S. cerevisiae, and P. chrysogenum (Ki = 18, 2500, and 1500 nM, respectively). Adenosine 5'-phosphosulfate also inhibits human adenosine 5'-phosphosulfate kinase (Ki = 47.5 μM) to prevent sulfation.
T80341	Seabream hepcidin
	Seabream hepcidin是一种抗菌肽，具有针对细菌(V.anguillarum)、真菌(S.cerevisiae)以及病毒性出血性败血症病毒的活性。
T37124	1,3-Dipalmitoleoyl-rac-glycerol
	1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. It selectively inhibits α-glucosidase from S. cerevisiae over rat enzyme (IC50s = 4.45 and 9,326.5 μM, respectively). 1,3-Dipalmitoleoyl-rac-glycerol has been used in the formation of lipid bilayers to study the effects of membrane composition and the ionophore valinomycin on membrane potential.
T83907	10-Chloroestra-1,4-diene-3,17-dione 10-chloro-1,4-Estradiene
	10-Chloroestra-1,4-diene-3,17-dione 是一个对雌性激素受体α (ERα) 具有激动作用的类固醇。它能增加在S. cerevisiae 中报告基因的表达（对人类受体的EC50 = 0.36 nM）。同时，它也是一种芳香化酶抑制剂（IC50 = 2.4 µM）。
T37286	1-Undecanoyl-rac-glycerol
	1-Undecanoyl-rac-glycerol is a monoacylglycerol that contains undecanoic acid at the sn-1 position. It completely inhibits the growth of the bacteria B. cereus, B. subtilis, M. luteus, E. faecalis, and S. aureus when used at concentrations ranging from 250 to 1,500 mg/L.1 1-Undecanoyl-rac-glycerol (0.1 and 0.3 mg/ml) also has antifungal activity against K. marxianus, S. cerevisiae, and C. maltosa.2
TP2192	Cdk2/Cyclin Inhibitory Peptide I	Others	Others
	Cyclin-dependent kinase 2 also known as cell division protein kinase 2. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar to the gene products of S. cerevis
T36336	Burnettramic Acid A
	Burnettramic acid A is a fungal metabolite originally isolated fromA. burnettiithat has diverse biological activities.1It is active againstB. subtilis,S. aureus,C. albicans, andS. cerevisiae(IC50s = 2.3, 5.9, 0.5, and 0.2 μg/ml, respectively). Burnettramic acid A is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 13.8 and >100 μg/ml, respectively). 1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic aci...
T38180	C16 Phytoceramide (t18:0/16:0)
	C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/16:0) is composed of a phytosphingosine backbone amine-linked to a C16 fatty acid chain. The levels of C16 phytoceramide (t18:0/16:0) increase following heat stress in S. cerevisiae. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous ...
T82088	ICMT-IN-54
	ICMT-IN-54 (compound 7c) 为一adamantyl类似物，具有ICMT抑制活性（IC50=12.4 μM），能够有效抑制ICMT的甲基转移作用。此化合物可在表达ICMT的酿酒酵母样本中阻断BFC甲基化，展现出间接抑制ICMT甲基化的能力。
T35781	Sphinganine (d20:0) Sphinganine (d20:0)
	Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well ...
T83815	6-Chloropurine riboside-5'-triphosphate sodium 6-chloro PuTP
	6-Chloropurine riboside-5'-triphosphate是一种RNA三磷酸酶mRNA-帽化酶β亚单位(Cet1; IC50 = 2 µM，针对S. cerevisiae酶的GTPase活性)的抑制剂，同时也是6-chloropurine riboside的磷酸化形式。此外，它还能激活E. coli天冬氨酸氨甲酰转移酶(EC50 = 0.76 mM)。6-Chloropurine riboside-5'-triphosphate已在合成具有抗癌活性的细胞因子以及一种光点击形式的ATP中得到应用。
T37458	C18 Phytoceramide (t18:0/18:0)
	C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TN...

化合物

Cat.No: T36533

Cat.No: T35769

Adenosine 5'-phosphosulfate (sodium salt)

Cat.No: T35574

Seabream hepcidin

Cat.No: T80341

1,3-Dipalmitoleoyl-rac-glycerol

Cat.No: T37124

10-Chloroestra-1,4-diene-3,17-dione

Cat.No: T83907

Synonym: 10-chloro-1,4-Estradiene

1-Undecanoyl-rac-glycerol

Cat.No: T37286

Cdk2/Cyclin Inhibitory Peptide I

Cat.No: TP2192

Target: Others

Burnettramic Acid A

Cat.No: T36336

C16 Phytoceramide (t18:0/16:0)

Cat.No: T38180

Cat.No: T82088

Sphinganine (d20:0)

Cat.No: T35781

Synonym: Sphinganine (d20:0)

6-Chloropurine riboside-5'-triphosphate sodium

Cat.No: T83815

Synonym: 6-chloro PuTP

C18 Phytoceramide (t18:0/18:0)

Cat.No: T37458

Cat. No.	Product Name	Target	Signaling Pathways
T37267	Pachybasin	Antibacterial	Microbiology/Virology
	Pachybasin 是一种蒽醌真菌代谢物。 Pachybasin 对大肠杆菌、枯草芽孢杆菌、M. luteus、S. cerevisiae、C. albicans、A. niger 和 A. flavus 具有抗菌活性，MIC 值为 64.0 μg/mL，对金黄色葡萄球菌具有抗菌活性和尖孢镰刀菌，MIC 值分别为 32.0 和 16.0 μg/mL。
T75676	Orotidine 5′-monophosphate trisodium
	Orotidine 5'-monophosphate trisodium 是一种嘧啶核苷酸。Orotidine 5'-monophosphate trisodium 是通过从头合成途径合成的，用于在大量微生物中合成 DNA，包括 M. tuberculosis、S. cerevisiae、S. typhimurium 和 P. falciparum 等等。乳清酸磷酸核糖基转移酶 (OPRT) 以磷酸核糖焦磷酸 (PRPP) 和乳清酸 (OA) 作为底物催化合成 Orotidine 5'-monophosphate trisodium[1]
T78500	α-Factor Mating Pheromone, yeast TFA Mating Factor α TFA
	α-Factor Mating Pheromone, yeast (TFA)为一来自S. cerevisiae的α细胞分泌的十三肽，通过Ste2p受体发挥作用。
T38086	Neohydroxyaspergillic Acid
	Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. mycoides, and B. subtilis bacteria (MICs = 125-500 μg/ml). Neohydroxyaspergillic acid also inhibits the growth of G. convolute, S. consortiale, P. blakesleeanus, C. globosum, and T. mentagrophytes (MICs = 175-700 μg/ml) but not A. niger, P. notatum, M. verrucaria, or S. cerevisiae ...
T38258	Phanerosporic Acid
	Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. niger, O. ulmi, U. maydis, C. cucmerinum, C. cladosporioides, and B. cinerea.1 It has been used in the synthesis of macrolide derivatives.References1. Arnone, A., Assante, G., Nasini, G., et al. Phanerosporic acid, a β-resorcylate obtained from Phanerochaete chrysosporium. Phytoch...
T37774	Thielavin A
	Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).

天然产物

Cat.No: T37267

Target: Antibacterial

Orotidine 5′-monophosphate trisodium

Cat.No: T75676

α-Factor Mating Pheromone, yeast TFA

Cat.No: T78500

Synonym: Mating Factor α TFA

Neohydroxyaspergillic Acid

Cat.No: T38086

Phanerosporic Acid

Cat.No: T38258

Cat.No: T37774

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04526	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His) Sec61 α1 subunit (S. cerevis<...	EBOV	E. coli
	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 44.1 kDa and the accession number is A0A2U8KL52.
TMPY-00312	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His) Sec61 α1 subunit (S. cerevis<...	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.6 kDa and the accession number is X5GXS8.
TMPY-00308	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His) Sec61 alpha 1 subunit (S. cerevi<...	EBOV	E. coli
	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A2U8KL52.
TMPH-03452	NDPK Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P36010.
TMPJ-01087	TIM14 Protein, S. cerevisiae, Recombinant Mitochondrial import inner membrane translocas<...	S. cerevisiae	E. coli
	Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as p...
TMPH-03454	GPM1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also Catalyzes the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. GPM1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.5 kDa and the accession number is P00950.
TMPH-03438	CHS1 Protein, S. cerevisiae, Recombinant (His) CHS1,Chitin-UDP acetyl-glucosaminyl tran	Saccharomyces cerevisiae	E. coli
	Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation during adverse conditions. CHS1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is P08004.
TMPH-03465	Kallikrein 15 Protein, S. cerevisiae, Recombinant (hFc)	Saguinus oedipus	HEK293 Cells
	Protease whose physiological substrate is not yet known. Kallikrein 15 Protein, S. cerevisiae, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 54.8 kDa and the accession number is Q7JIG6.
TMPH-03458	STE11 Protein, S. cerevisiae, Recombinant	Saccharomyces cerevisiae	E. coli
	Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases. STE11 Protein, S. cerevisiae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.5 kDa and the accession number is P23561.
TMPJ-00965	TIM16 Protein, S. cerevisiae, Recombinant TIM16,Mitochondrial import inner membrane transloca...	S. cerevisiae	E. coli
	Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM16 is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. TIM16 may act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase s...
TMPY-03344	LSM3 Protein, Human, Recombinant (His) SMX4,YLR438C,USS2,LSM3 h...	Human	E. coli
	LSM3 (LSM3 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. LSM3 is a member of the snRNP Sm proteins family. It plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as a component of the pre-catalytic spliceosome (spliceosome B complex). Sm-like proteins can be detected in a variety of organisms. They all have the Sm sequence motif, which consists of 2 regions separated by a linker ...
TMPH-03433	ACB1 Protein, S. cerevisiae, Recombinant (His) Acyl-CoA-binding protein	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. ACB1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.1 kDa and the accession number is P31787.
TMPH-03437	CDA2 Protein, S. cerevisiae, Recombinant (His) CDA2,Chitin deacetylase 2	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is a component of the spore wall. CDA2 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q06703.
TMPH-03448	EHT1 Protein, S. cerevisiae, Recombinant (His) EHT1,Ethanol hexanoyl transferase 1,Alcoho...	Saccharomyces cerevisiae	E. coli
	Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification. EHT1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 57.3 kDa and the accession number is P38295.
TMPH-03442	PMT5 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT3 and more rarely with PMT2 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT5 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.6 kDa and the accession number is P52867.
TMPH-03461	IFM1 Protein, S. cerevisiae, Recombinant (GST)	Saccharomyces cerevisiae	E. coli
	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. IFM1 Protein, S. cerevisiae, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 97.5 kDa and the accession number is P25038.
TMPH-03430	ECM31 Protein, S. cerevisiae, Recombinant (His) Extracellular matrix protein 31,Ketopantoate hydroxymethyltr...	Saccharomyces cerevisiae	E. coli
	ECM31 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.5 kDa and the accession number is P38122.
TMPH-03444	GCY1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity. GCY1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.1 kDa and the accession number is P14065.
TMPH-03447	ERG11 Protein, S. cerevisiae, Recombinant (GST)	Saccharomyces cerevisiae	E. coli
	Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. ERG11 Protein, S. cerevisiae, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 29.1 kDa and the accession number is P10614.
TMPH-03450	Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant	Saccharomyces cerevisiae	E. coli
	Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.0 kDa and the accession number is P53184.
TMPH-03441	PMT3 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT5 and more rarely with PMT1 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. Seems to have redundant activity to PMT2. PMT3 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is P47190.
TMPH-03459	FLP1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	FLP1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.1 kDa and the accession number is P03870.
TMPH-03429	DOG1 Protein, S. cerevisiae, Recombinant (His) DOG1,2-DOG-6-P 1,2-deoxyglucose-6-phosphat...	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Active on 2-DOG-6P, also very active on fructose-1P. DOG1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is P38774.
TMPH-03439	STE13 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	Responsible for the proteolytic maturation of the alpha-factor precursor. STE13 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.0 kDa and the accession number is P33894.
TMPH-03462	SMT3 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Not known; suppressor of MIF2 mutations.
TMPH-03436	MNT3 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	Baculovirus Insect Cells
	Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans. MNT3 Protein, S. cerevisiae, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 71.2 kDa and the accession number is P40549.
TMPH-03464	SUS1 Protein, S. cerevisiae, Recombinant (His & SUMO)	Saccharum officinarum	E. coli
	Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. SUS1 Protein, S. cerevisiae, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is P31925.
TMPH-03434	BIO3 Protein, S. cerevisiae, Recombinant (His & Myc) Diaminopelargonic acid synthase,BIO3,7,8-d...	Saccharomyces cerevisiae	E. coli
	Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor. BIO3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.7 kDa and the accession number is P50277.
TMPH-03445	GSP1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	P. pastoris (Yeast)
	GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Essential for cell viability. By analogy with Ras, Ran may be activated when GTP is exchanged for bound GDP by RCC1 and inactivated when GTP is hydrolyzed by Ran upon activation by RanGAP1. GSP1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P32835.
TMPH-03456	CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) CAK1,CIV1,Serine/threonine-protein kinase ...	Saccharomyces cerevisiae	Baculovirus Insect Cells
	CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 46.1 kDa and the accession number is P43568.
TMPH-03451	NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)	Saccharomyces cerevisiae	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P36010.
TMPH-03440	RAD52 Protein, S. cerevisiae, Recombinant (His & SUMO)	Saccharomyces cerevisiae	E. coli
	Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. RAD52 Protein, S. cerevisiae, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.1 kDa and the accession number is P06778.
TMPH-03443	GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the presence of Ca(2+). Has peroxidase activity using preferentially thioredoxin as a reducing power. The redox state of the mitochondrial GPX2 is regulated by TRX1 and TRX2 (cytoplasmic thioredoxin), and by TRX3 (mitochondrial matrix thioredoxin). Involved in sporulation. GPX2 Protein, ...
TMPH-03453	GPI3 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. GPI3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.8 kDa and the accession number is P32363.
TMPH-03449	Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.0 kDa and the accession number is P53184.
TMPH-03446	SSA1 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	May play a role in the transport of polypeptides both across the mitochondrial membranes and into the endoplasmic reticulum. A functional difference between SSA1 and SSA2 proteins is expected. SSA1 can participate in the ATP-dependent disassembly of clathrin-coated vesicles. SSA1 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.3 kDa and the accession number is P10591.
TMPH-03460	ERG26 Protein, S. cerevisiae, Recombinant (His & Myc)	SVG-Saccharomyces cerevisiae	E. coli
	Essential enzyme in the ergosterol biosynthetic pathway. Part of a 3 enzyme system that catalyzes the sequential removal of the 2 methyl groups at the sterol C-4 position, converting 4,4-dimethylzymosterol to zymosterol. Catalyzes the second step, an oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group. ERG26 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre...
TMPH-03463	SMT3 Protein, S. cerevisiae, Recombinant (His & SUMO)	Saccharomyces cerevisiae	E. coli
	Not known; suppressor of MIF2 mutations.
TMPH-03455	Polyphosphatase/PPX1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	Degradation of inorganic polyphosphates.
TMPH-03432	ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) mRNA transport-defective protein 7,Acetyl-CoA carbo...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol...
TMPH-03457	CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) Serine/threonine-protein kinase CAK1,CAK1,...	Saccharomyces cerevisiae	E. coli
	CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P43568.
TMPH-03435	MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His)	Saccharomyces cerevisiae	E. coli
	Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans. MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 74.7 kDa and the accession number is P40549.
TMPH-03431	ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) Acetyl-CoA carboxylase,ACC,Fatty acid synt...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m...
TMPY-04548	CDK4 Protein, Human, Recombinant (GST) CMM3,PSK-J3,cyclin-dependent kinase 4	Human	Baculovirus Insect Cells
	CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of CDK4 is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). CDK4 was shown to be responsible for the phosphorylation of retinoblastoma gene product. CDK4 is the ser...
TMPY-04542	CDK2 Protein, Human, Recombinant (His) CDKN2,cyclin-dependent kinase 2,p33(CDK2)	Human	Baculovirus Insect Cells
	CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the c...
TMPY-01306	DNMT2 Protein, Human, Recombinant (GST) PUMET,RNMT1,tRNA aspartic acid methyltrans...	Human	Baculovirus Insect Cells
	DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evolution and contain all of the signature motifs of DNA (cytosine-5)-methyltransferases. It contains all 10 sequence motifs that are conserved among m(5)C MTases, including the consensus S:-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide, and its structure...

重组蛋白

Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His)

Cat.No: TMPY-04526

Species: EBOV

Expression System: E. coli

Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His)

Cat.No: TMPY-00312

Species: EBOV

Expression System: E. coli

Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His)

Cat.No: TMPY-00308

Species: EBOV

Expression System: E. coli

NDPK Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03452

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

TIM14 Protein, S. cerevisiae, Recombinant

Cat.No: TMPJ-01087

Species: S. cerevisiae

Expression System: E. coli

GPM1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03454

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

CHS1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03438

Species: Saccharomyces cerevisiae

Expression System: E. coli

Kallikrein 15 Protein, S. cerevisiae, Recombinant (hFc)

Cat.No: TMPH-03465

Species: Saguinus oedipus

Expression System: HEK293 Cells

STE11 Protein, S. cerevisiae, Recombinant

Cat.No: TMPH-03458

Species: Saccharomyces cerevisiae

Expression System: E. coli

TIM16 Protein, S. cerevisiae, Recombinant

Cat.No: TMPJ-00965

Species: S. cerevisiae

Expression System: E. coli

LSM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03344

Species: Human

Expression System: E. coli

ACB1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03433

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

CDA2 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03437

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

EHT1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03448

Species: Saccharomyces cerevisiae

Expression System: E. coli

PMT5 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03442

Species: Saccharomyces cerevisiae

Expression System: E. coli

IFM1 Protein, S. cerevisiae, Recombinant (GST)

Cat.No: TMPH-03461

Species: Saccharomyces cerevisiae

Expression System: E. coli

ECM31 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03430

Species: Saccharomyces cerevisiae

Expression System: E. coli

GCY1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03444

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

ERG11 Protein, S. cerevisiae, Recombinant (GST)

Cat.No: TMPH-03447

Species: Saccharomyces cerevisiae

Expression System: E. coli

Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant

Cat.No: TMPH-03450

Species: Saccharomyces cerevisiae

Expression System: E. coli

PMT3 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03441

Species: Saccharomyces cerevisiae

Expression System: E. coli

FLP1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03459

Species: Saccharomyces cerevisiae

Expression System: E. coli

DOG1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03429

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

STE13 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03439

Species: Saccharomyces cerevisiae

Expression System: E. coli

SMT3 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03462

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

MNT3 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03436

Species: Saccharomyces cerevisiae

Expression System: Baculovirus Insect Cells

SUS1 Protein, S. cerevisiae, Recombinant (His & SUMO)

Cat.No: TMPH-03464

Species: Saccharum officinarum

Expression System: E. coli

BIO3 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03434

Species: Saccharomyces cerevisiae

Expression System: E. coli

GSP1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03445

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

CAK1 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03456

Species: Saccharomyces cerevisiae

Expression System: Baculovirus Insect Cells

NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)

Cat.No: TMPH-03451

Species: Saccharomyces cerevisiae

Expression System: E. coli

RAD52 Protein, S. cerevisiae, Recombinant (His & SUMO)

Cat.No: TMPH-03440

Species: Saccharomyces cerevisiae

Expression System: E. coli

GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03443

Species: Saccharomyces cerevisiae

Expression System: E. coli

GPI3 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03453

Species: Saccharomyces cerevisiae

Expression System: E. coli

Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03449

Species: Saccharomyces cerevisiae

Expression System: E. coli

SSA1 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03446

Species: Saccharomyces cerevisiae

Expression System: E. coli

ERG26 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03460

Species: SVG-Saccharomyces cerevisiae

Expression System: E. coli

SMT3 Protein, S. cerevisiae, Recombinant (His & SUMO)

Cat.No: TMPH-03463

Species: Saccharomyces cerevisiae

Expression System: E. coli

Polyphosphatase/PPX1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03455

Species: Saccharomyces cerevisiae

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

Cat.No: TMPH-03432

Species: Saccharomyces cerevisiae

Expression System: E. coli

CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03457

Species: Saccharomyces cerevisiae

Expression System: E. coli

MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His)

Cat.No: TMPH-03435

Species: Saccharomyces cerevisiae

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

Cat.No: TMPH-03431

Species: Saccharomyces cerevisiae

Expression System: E. coli

CDK4 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04548

Species: Human

Expression System: Baculovirus Insect Cells

CDK2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04542

Species: Human

Expression System: Baculovirus Insect Cells

DNMT2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01306

Species: Human

Expression System: Baculovirus Insect Cells

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